[快报]2009年诺贝尔生理与医学奖揭晓

The Nobel Prize in Physiology or Medicine 2009

得奖的是3个美国的科学家,分别是

Elizabeth H. Blackburn (女,生于1948 于Hobart, Tasmania, Australia)
University of California, San Francisco, CA, USA

Carol W. Greider (女,生于1961)
Johns Hopkins University School of Medicine, Baltimore, MD, USA

Jack W. Szostak (男,生于1952,于London, United Kingdom)
Howard Hughes Medical Institute; Harvard Medical School; Massachusetts General Hospital, Boston, MA, USA

其主要成就在于:他们发现了端粒和端粒酶是如何保护染色体的("for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase" )。报道他们发现的最初几篇paper是:

1.  Szostak JW, Blackburn EH. Cloning yeast telomeres on linear plasmid vectors. Cell 1982; 29:245-255.
2. Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985; 43:405-13.
3. Greider CW, Blackburn EH. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 1989; 337:331-7.

详细资料,可参考这个pdf文档(667 KB, 来自Nobelprize.org) 。更详细的中文报道见丁香园